Laboratory of Genomics
718.752.4637
Email molecular@nybloodcenter.org

The Laboratory offers genomic DNA testing for platelet and neutrophil antigens. DNA molecular testing can improve platelet typing accuracy, help select compatible donors, aid the management and treatment for neonatal platelet destruction, and improve transfusion safety and outcomes for patients.

Indications:

• Testing for platelet antigens and post-transfusion purpura (PTP)
• Evaluation of fetal risk for alloimmune thrombocytopenia (NAIT) due to maternal antibodies to platelet antigens Including:
• Determine maternal HPA type
• Determine paternal HPA type
• Typing of fetal amniocytes or chorionic villus sample (CVS)

Typing for the following platelet antigens is available:

• HPA-1a/1b
• HPA- 2a/2b (Ko)
• HPA-3a/3b (Bak)
• HPA -4a/4b (Pen)
• HPA-5a/5b (Br)
• HPA-15a/15b (Gov)
• HPA Panel: includes HPA 1 through 9, 11, and 15