NYBC's Laboratory of Immunohematology and Genomics provides reference laboratory services and consultation to assist hospitals in the resolution of patient antibody problems and to locate suitable units of blood for transfusion. The laboratory maintains one of the largest collections of well-characterized red cells to identify antibodies and one of the largest inventories of liquid and frozen donor units to support patients who need antigen-negative units for transfusion. The laboratory also participates in the American Rare Donor Program (ARDP) to find rare blood that cannot be found locally.
The laboratory, under the direction of Connie Westhoff, PhD(CWesthoff@nybloodcenter.org), receives more than 1,800 requests annually from hospitals and blood centers nationwide for help in identifying antibodies, and over 20 requests daily for assistance in matching donors to patients. The laboratory relies on the skill of a number of experienced and nationally recognized technologists.
Immunohematology testing services include investigation of:
The Genomics Laboratory offers testing of DNA and RNA for blood group antigens and DNA testing for platelet and neutrophil antigens. DNA molecular testing can improve blood typing accuracy, help select compatible donors, aid the management and treatment for neonatal red cell or platelet destruction, and improve transfusion safety and outcomes for patients. The laboratory employs methods that include DNA array, PCR-RFLP, AS-PCR and gene specific amplification and sequencing. Isolation of mRNA and synthesis and sequencing of cDNA is also performed when indicated. The results are interpreted by staff experienced and knowledgeable in genetics and immunohematology.
Genomics testing services include:
Indications for DNA Testing
Fetal or Neonatal Testing