Our program provides cord blood in the following usage and product categories:
- For Transplantation: HEMACORD® (HPC, Cord Blood), FDA-licensed hematopoietic stem cell product available to transplant centers worldwide. In addition, NCBP has an extensive inventory of clinical-grade units available under an Investigational New Drug (IND) exemption from the FDA
- For Cellular Therapies: Stem cells for use in clinical trials, provided on a case-by-case basis
- For Research: Processed and unprocessed cord blood for research use by academic, instutional and commercial users
HEMACORD® and IND units are available directly to transplant centers and registries through WebSearch™, our proprietary secure online interactive tool. WebSearch™ can be used to register patients, search for cord blood units (CBUs), view all information related to a CBU, reserve a CBU, order testing or additional information, and place an order for shipment. There is no cost to register, and once complete, you will be contacted by our coordinators to provide interactive online training and complete the registration process.
HEMACORD® the First FDA-Licensed Stem Cell Product
HEMACORD® (HPC, Cord Blood) consists of hematopoietic progenitor cells, monocytes, lymphocytes, and granulocytes from human cord blood. Blood recovered from umbilical cord and placenta is volume reduced and partially depleted of red blood cells and plasma.
For complete information on Indications and Usage, Contraindications, Important Safety Information, Warnings and Precautions, and Adverse Reactions, please visit our full product website.
Investigational New Drug (IND) Cord Blood Units
In 1996, we became the first cord blood bank to receive an IND exemption from the FDA. Our extensive inventory of clinical-grade, IND units is available for distribution directly to over 60 leading transplant centers worldwide, as well as through major international registries.
How to Request a Cord Blood Unit
Most major transplant centers submit “Search Requests” directly to our program using our proprietary online search platform called Web Search. From there, our staff of experts coordinates the identification, testing and transport of cord blood units to national and international transplant centers.
In addition to our online platform, transplant centers have two other indirect means for searching and procuring from our inventory:
- The National Marrow Donor Program (NMDP) operates the Be the Match™ Registry which serves as the single point of access for the National Cord Blood Inventory (as described under the federally-sponsored C.W. Bill Young Cell Transplantation Program). Out entire clinical inventory, including those designated for the National Cord Blood Inventory, is available on the Be the Match™ search database.
- The World Marrow Donor Association (WMDA) maintains an international registry of bone marrow donors and cord blood units, and its search engine finds matches and provides requesting transplant centers the IDs and banks (or registries) of the matched bone marrow or cord blood donors.
For Cellular Therapies
Our program is an active participant in several clinical and non-clinical research trials. Given our extensive inventory, associated stored samples, test results and database containing hundreds of variables on each unit, we provide complete customization for research trial needs.
We are interested to participate in additional cord blood-derived cellular therapies that aim to improve patient outcomes. For our products to be used in such studies, the proposed cell therapy will have to meet all current requirements for clinical use, including an IRB approval and an IND from the FDA.
For Research Use
Cord blood units (CBUs) are collected primarily for clinical use, but sometimes do not meet all criteria to be licensed HEMACORD or used in a patient under an Investigational New Drug application.
CBUs that do not meet these criteria are made available to scientists at many academic, institutional and commercial organizations for important basic and applied research on stem and immune cells. We obtain research use consent from the donating mother for all units offered for non-clinical use. Our extensive inventory of high quality research products includes:
- Fresh, non-clinical grade CBUs. These CBUs are neither processed, other than mixed with anticoagulant, nor tested and they are provided without donor identifiers or donor specific information
- Frozen research CBUs have been volume-reduced to remove most of the red blood cells and plasma and have been concentrated to 25 mL final volume, including the cryoprotectant. They have been frozen using the controlled-rate method and are stored in liquid nitrogen in BioArchive freezers. Frozen CBUs have had at least some testing performed, e.g., Infectious Disease Markers, HLA, Bacteriology, Flow Cytometry, and CBC. Frozen CBUs with specifically desired characteristics, such as total cell count, CD34+ count or HLA typing, can be provided upon request